Rat Striatin-3 (STRN3) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Rat Striatin-3 (STRN3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx547799
tested applications
ELISA
Description
Rat Striatin-3 (STRN3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Striatin-3 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Striatin-3 (STRN3) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P58405 |
| Alias | PPP2R6B,S/G2NA,SG2NA,Cell cycle autoantigen SG2NA,S/G2 antigen |
| Background | Elisa kits for STRN3 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Striatin-3 (STRN3), also known as SG2NA, is a member of the striatin family that functions as a scaffolding protein within the STRIPAK complex. STRN3 coordinates signaling events by interacting with PP2A, kinases, and other regulatory proteins to regulate cell signaling, cytoskeletal dynamics, and vesicular trafficking. It is expressed in various tissues, particularly in the brain, where it modulates calcium-calmodulin signaling pathways essential for neurodevelopment, synaptic plasticity, and neuronal communication. STRN3 plays additional roles in endothelial cell function, angiogenesis, and cell migration through its interactions with signaling proteins. Dysregulation of STRN3 has been implicated in cancers and neurological disorders, where altered PP2A activity and disrupted signaling pathways contribute to disease progression. Functional studies reveal that loss of STRN3 impairs cellular signaling, cytoskeletal reorganization, and vesicle transport, emphasizing its role in cellular communication, cytoskeletal integrity, and signaling homeostasis.
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