Rat Retinoic acid receptor RXR-alpha (RXRA) ELISA Kit
715€ (96 tests)
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Name
Rat Retinoic acid receptor RXR-alpha (RXRA) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx519223
Tested Applications
ELISA
Description
Rat Retinoic acid receptor RXR-alpha (RXRA) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Retinoic acid receptor RXR-alpha concentrations in tissue homogenates, cell lysates and other biological fluids.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | Retinoic acid receptor RXR-alpha (RXRA) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q05343 |
| Alias | NR2B1,RXRalpha,RXR-alpha,Retinoic acid receptor RXR-alpha,Nuclear receptor subfamily 2 group B member 1,Retinoid X receptor alpha |
| Background | Elisa Kits for: RXRA |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Background
Retinoid X receptor alpha (RXRA) is a nuclear receptor that plays a crucial role in regulating gene expression in response to retinoids, which are derived from vitamin A RXRA forms heterodimers with other nuclear receptors, such as the retinoic acid receptor (RAR) and peroxisome proliferator-activated receptors (PPARs), to regulate genes involved in processes such as cell differentiation, metabolism, and immune responses RXRA is involved in the regulation of lipid metabolism, glucose homeostasis, and cellular growth and differentiation It also plays a role in the development and maintenance of the central nervous system and immune system RXRA’s activity is essential for maintaining metabolic balance and preventing diseases like cancer, cardiovascular disease, and metabolic disorders, as it regulates critical pathways in cellular growth and lipid homeostasis Dysregulation of RXRA signaling has been linked to various cancers, including breast and prostate cancers, as well as metabolic diseases and disorders related to vitamin A deficiency RXRA is also a target for therapies aimed at controlling metabolic and inflammatory diseases
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