Rat Ras-Related protein Rab-35 (RAB35) ELISA Kit

Rat Ras-Related protein Rab-35 (RAB35) ELISA Kit
715€ (96 tests)

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Name
Rat Ras-Related protein Rab-35 (RAB35) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx541141
Tested Applications
ELISA

Description

Rat Ras-Related protein Rab-35 (RAB35) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Ras-related protein Rab-35 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Ras-Related protein Rab-35 (RAB35)
Reactivity
Rat
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q5U316
Alias
RAY,H-ray,RAB1C,Ras-related protein Rab-1C,GTP-binding protein RAY,Ras-related protein Rab-35
Background
Elisa Kits for: RAB35
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

RAB35, member RAS oncogene family (RAB35) is a small GTPase involved in regulating endocytosis, vesicle trafficking, and membrane recycling in the cell It plays an essential role in the trafficking of cellular membranes and proteins, particularly in the sorting of endosomal cargo for recycling or degradation RAB35 is also crucial in the regulation of autophagy, where it helps in the formation of autophagosomes for the degradation of dysfunctional cellular components This GTPase is involved in cellular signaling by modulating the movement of receptors and other signaling molecules to and from the cell membrane, thus influencing cell communication, adhesion, and migration RAB35’s dysfunction can result in impaired cellular homeostasis, contributing to diseases such as cancer, where disrupted vesicular trafficking supports uncontrolled cell growth and metastasis Moreover, defects in RAB35 are also linked to neurodegenerative conditions, where defective vesicular trafficking leads to cellular stress and dysfunction

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