RAB35, Member RAS Oncogene Family (RAB35) Antibody
260€ (50 µl)
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Name
RAB35, Member RAS Oncogene Family (RAB35) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx214630
Tested Applications
ELISA, IHC
Description
RAB35 Antibody is a Rabbit Polyclonal against RAB35.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: RAB35, Member RAS Oncogene Family (RAB35) Immunogen: Synthetic peptide of human RAB35. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/1000 - 1/5000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q15286 |
| Gene ID | 11021 |
| Alias | RAY,H-ray,RAB1C,Ras-related protein Rab-1C,GTP-binding protein RAY,Ras-related protein Rab-35 |
| Background | Antibody anti-RAB35 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
RAB35, member RAS oncogene family (RAB35) is a small GTPase involved in regulating endocytosis, vesicle trafficking, and membrane recycling in the cell It plays an essential role in the trafficking of cellular membranes and proteins, particularly in the sorting of endosomal cargo for recycling or degradation RAB35 is also crucial in the regulation of autophagy, where it helps in the formation of autophagosomes for the degradation of dysfunctional cellular components This GTPase is involved in cellular signaling by modulating the movement of receptors and other signaling molecules to and from the cell membrane, thus influencing cell communication, adhesion, and migration RAB35’s dysfunction can result in impaired cellular homeostasis, contributing to diseases such as cancer, where disrupted vesicular trafficking supports uncontrolled cell growth and metastasis Moreover, defects in RAB35 are also linked to neurodegenerative conditions, where defective vesicular trafficking leads to cellular stress and dysfunction
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