Rat P2Y Purinoceptor 12 (P2RY13) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for P2RY13
proveedor
Abbexareference
abx537473Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Purinergic Receptor P2Y13 (P2RY13) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat P2Y purinoceptor 13 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
P2RY13 is a G protein-coupled receptor primarily activated by ADP and related nucleotides. It couples to Gi proteins, inhibiting adenylate cyclase, reducing cAMP levels, and modulating downstream cellular responses. P2RY13 is expressed in immune cells, liver, and the central nervous system, where it regulates lipid metabolism, immune responses, and energy homeostasis. In the liver, P2RY13 plays a key role in cholesterol metabolism by mediating the uptake of high-density lipoproteins (HDL), contributing to cholesterol homeostasis. In immune cells, P2RY13 regulates chemotaxis, cytokine production, and inflammation. Dysregulation of P2RY13 has been linked to lipid disorders, atherosclerosis, and inflammatory diseases. Its role in immune and metabolic regulation makes P2RY13 a promising therapeutic target for managing hyperlipidemia, atherosclerosis, and chronic inflammatory conditions. Understanding its signaling mechanisms could provide novel therapeutic avenues for metabolic and immune-related diseases.
Características del producto
category
ELISA Kits
immunogen target
P2Y Purinoceptor 12 (P2RY13)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
P2RY13,GPR94,G protein-coupled receptor 86,P2Y purinoceptor 13, purinergic receptor P2Y G-protein coupled 13,purinergic receptor P2Y,FKSG77,GPCR1,GPR86,P2Y13,SP174
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
P2RY13
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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proveedor
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human,mousestatus
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