Rat Prostaglandin F2-Alpha Receptor (PTGFR) ELISA Kit

Name: Rat Prostaglandin F2-Alpha Receptor (PTGFR) ELISA Kit
Brand: Abbexa
SKU: abx353865
Price: 611 EUR
Availability: OnlineOnly

Este producto es parte de PTGR - Prostaglandin receptor

611€ (96 tests)

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Rat Prostaglandin F2-Alpha Receptor (PTGFR) ELISA Kit

Description

Rat Prostaglandin F2-Alpha Receptor (PTGFR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Prostaglandin F Receptor concentrations in tissue homogenates, cell lysates and other biological fluids.

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Product specifications

Category	ELISA Kits
Immunogen Target	Prostaglandin F2-Alpha Receptor (PTGFR)
Reactivity	Rat
Detection Method	Colorimetric
Assay Data	Quantitative
Assay Type	Sandwich
Test Range	0.78 ng/ml - 50 ng/ml
Sensitivity	0.47 ng/ml
Recommended Dilution	Optimal dilutions/concentrations should be determined by the end user.
Size 1	96 tests
Size 2	5 × 96 tests
Size 3	10 × 96 tests
Form	Lyophilized
Tested Applications	ELISA
Sample Type	Tissue homogenates, cell lysates and other biological fluids.
Availability	Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage	Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice	No
UniProt ID	P43118
Gene ID	25652
Alias	PTGFR,PF2AR,PGF receptor,PGF2 alpha receptor,prostaglandin F receptor,prostaglandin F2-alpha receptor,prostaglandin F receptor,FP
Background	Elisa kits for PTGFR
Status	RUO
Note	Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Prostaglandin F2-Alpha Receptor (PTGFR), also known as the FP receptor, is a G protein-coupled receptor activated by prostaglandin F2-alpha (PGF2α), a lipid-derived signaling molecule involved in reproductive, vascular, and inflammatory processes. PTGFR primarily couples to Gq proteins, activating phospholipase C (PLC), increasing intracellular calcium, and stimulating downstream signaling pathways, including Rho-kinase and MAPK. PTGFR is widely expressed in the uterus, corpus luteum, vascular smooth muscle, and ocular tissues, where it regulates smooth muscle contraction, luteolysis, and intraocular pressure. In the female reproductive system, PTGFR mediates uterine contraction during labor and luteolysis, the regression of the corpus luteum, which is essential for the estrous cycle. Clinically, FP receptor agonists such as latanoprost and bimatoprost are widely used to treat glaucoma by reducing intraocular pressure through enhanced aqueous humor outflow. Dysregulation of PTGFR signaling is associated with preterm labor, dysmenorrhea, and elevated intraocular pressure. Due to its role in smooth muscle regulation and ocular function, PTGFR remains a critical therapeutic target for reproductive and ophthalmic disorders.

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