Rat Prostaglandin D2 Receptor 2 (PTGDR2) ELISA Kit
715€ (96 tests)
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935106861
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name
Rat Prostaglandin D2 Receptor 2 (PTGDR2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx538139
tested applications
ELISA
Description
Rat Prostaglandin D2 Receptor 2 (PTGDR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Prostaglandin D2 receptor 2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Prostaglandin D2 Receptor 2 (PTGDR2) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q6XKD3 |
| Alias | PTGDR2,CRTH2,CD294,G protein-coupled receptor 44, prostaglandin D2 receptor 2,PGD2 receptor,Gpr44,DL1R, DP2 |
| Background | Elisa kits for PTGDR2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
PTGDR2, also known as DP2 or CRTH2 (chemoattractant receptor-homologous molecule expressed on Th2 cells), is a G protein-coupled receptor that binds prostaglandin D2 (PGD2). Unlike PTGDR, PTGDR2 couples to Gi proteins, inhibiting adenylate cyclase and promoting calcium mobilization, leading to chemotaxis, immune activation, and inflammation. PTGDR2 is highly expressed in Th2 cells, eosinophils, basophils, and innate lymphoid cells (ILC2), where it mediates allergic inflammation, cytokine release, and recruitment of immune cells to inflamed tissues. PTGDR2 is a key player in Th2-driven diseases, including asthma, allergic rhinitis, and chronic obstructive pulmonary disease (COPD). Dysregulation of PTGDR2 signaling contributes to chronic airway inflammation, tissue remodeling, and eosinophilic responses. PTGDR2 antagonists are being developed as novel therapies for allergic asthma, atopic dermatitis, and other Th2-mediated inflammatory conditions by inhibiting PGD2-dependent immune cell activation.
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