Rat Oxysterols Receptor LXR-Beta (NR1H2) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits NR1H2
proveedor
Abbexareference
abx354223Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Oxysterols Receptor LXR-Beta (NR1H2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Oxysterols Receptor LXR-Beta (NR1H2) concentrations in Tissue homogenates, cell lysates and other biological fluids.
Background
Nuclear receptor subfamily 1 group H member 2 (NR1H2), also known as LXRα (liver X receptor alpha), is a nuclear receptor involved in regulating lipid metabolism, cholesterol homeostasis, and immune response NR1H2 is primarily expressed in tissues such as the liver, adipose tissue, and macrophages, where it regulates genes involved in the absorption, storage, and catabolism of cholesterol and lipids LXRα plays a key role in maintaining cholesterol balance by promoting the expression of genes that enhance cholesterol efflux and inhibit cholesterol biosynthesis It also regulates inflammatory pathways, influencing the immune system's response to atherosclerosis and other chronic inflammatory diseases Dysregulation of NR1H2 signaling has been associated with cardiovascular diseases, such as atherosclerosis, where improper lipid metabolism leads to the accumulation of cholesterol plaques in blood vessels LXRα is also a potential therapeutic target for managing metabolic diseases, inflammation, and lipid-related disorders
Características del producto
category
ELISA Kits
immunogen target
Oxysterols Receptor LXR-Beta (NR1H2)
reactivity
Rat
test range
62.5 pg/ml - 4000 pg/ml
sensitivity
37.5 pg/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
NER,UNR,LXRB,LXR-b,NER-I,RIP15,Oxysterols receptor LXR-beta,Liver X receptor beta,Nuclear receptor NER
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
NR1H2
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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