Rat Nucleoporin 107 kDa (NUP107) ELISA Kit

Este producto es parte de NUP - nucleoporin
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611€ (96 tests)

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935106861
info@markelab.com
name
Rat Nucleoporin 107 kDa (NUP107) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx353804
tested applications
ELISA

Description

Rat Nucleoporin 107 kDa (NUP107) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Nucleoporin 107 kDa (NUP107) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Nucleoporin 107 kDa (NUP107)
Reactivity
Rat
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.78 ng/ml - 50 ng/ml
Sensitivity
0.47 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P52590
Alias
ODG6,NUP84,NPHS11,ODG6,GAMOS7,nucleoporin 107kDa,nuclear pore complex protein Nup107
Background
Elisa kits for NUP107
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Nucleoporin 107 (NUP107) is an integral part of the nuclear pore complex, where it plays a crucial role in the assembly and function of the pore NUP107 interacts with other nucleoporins to form the central scaffold of the pore, contributing to the selective passage of molecules, such as RNA and proteins, between the nucleus and cytoplasm NUP107 is also involved in the regulation of the cell cycle and DNA repair by ensuring proper nuclear-cytoplasmic exchange of cell cycle regulators and repair proteins Its function is critical for maintaining cellular homeostasis, as defects in nucleocytoplasmic transport can lead to diseases such as cancer and neurodegenerative disorders Dysregulation of NUP107 has been linked to increased susceptibility to genetic instability, tumor formation, and poor prognosis in several cancers Additionally, NUP107 plays a role in the maintenance of the nuclear envelope, supporting nuclear structure and stability during cell division

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