Nucleoporin 107 (NUP107) Antibody
52€ (10 µg)
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Name
Nucleoporin 107 (NUP107) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx014671
Tested Applications
WB
Description
Rabbit polyclonal antibody against NUP107 protein. Immunogen region is Internal.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Nucleoporin 107 (NUP107) Immunogen: The antiserum was produced against synthesized peptide derived from Internal of human NUP107. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P57740 |
| Alias | ODG6,NUP84,NPHS11,ODG6,GAMOS7,nucleoporin 107kDa,nuclear pore complex protein Nup107 |
| Background | Antibody anti-NUP107 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Nucleoporin 107 (NUP107) is an integral part of the nuclear pore complex, where it plays a crucial role in the assembly and function of the pore NUP107 interacts with other nucleoporins to form the central scaffold of the pore, contributing to the selective passage of molecules, such as RNA and proteins, between the nucleus and cytoplasm NUP107 is also involved in the regulation of the cell cycle and DNA repair by ensuring proper nuclear-cytoplasmic exchange of cell cycle regulators and repair proteins Its function is critical for maintaining cellular homeostasis, as defects in nucleocytoplasmic transport can lead to diseases such as cancer and neurodegenerative disorders Dysregulation of NUP107 has been linked to increased susceptibility to genetic instability, tumor formation, and poor prognosis in several cancers Additionally, NUP107 plays a role in the maintenance of the nuclear envelope, supporting nuclear structure and stability during cell division
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