NUP107 antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
NUP107 antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab05919
Tested Applications
ELISA, WB
Description
Plays a role in the nuclear pore complex(NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC.
Documentos del producto
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | nucleoporin 107kDa (NUP107) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 107 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P57740 |
| Gene ID | 57122 |
| Alias | ODG6,NUP84,NPHS11,ODG6,GAMOS7,nucleoporin 107kDa,nuclear pore complex protein Nup107 |
| Background | Antibody anti-NUP107 |
| Status | RUO |
| Note | Mol. Weight 107 kDa |
Background
Nucleoporin 107 (NUP107) is an integral part of the nuclear pore complex, where it plays a crucial role in the assembly and function of the pore NUP107 interacts with other nucleoporins to form the central scaffold of the pore, contributing to the selective passage of molecules, such as RNA and proteins, between the nucleus and cytoplasm NUP107 is also involved in the regulation of the cell cycle and DNA repair by ensuring proper nuclear-cytoplasmic exchange of cell cycle regulators and repair proteins Its function is critical for maintaining cellular homeostasis, as defects in nucleocytoplasmic transport can lead to diseases such as cancer and neurodegenerative disorders Dysregulation of NUP107 has been linked to increased susceptibility to genetic instability, tumor formation, and poor prognosis in several cancers Additionally, NUP107 plays a role in the maintenance of the nuclear envelope, supporting nuclear structure and stability during cell division
Productos relacionados
Nucleoporin 107 (NUP107) Antibody
Rabbit polyclonal antibody against NUP107 protein. Immunogen region is Internal.…
Ver producto
Nucleoporin 107 (NUP107) Antibody
This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential co…
Ver producto
Mouse Nucleoporin 107 kDa (NUP107) Protein
Mouse Nucleoporin 107 kDa (NUP107) is a recombinant Mouse protein expressed in E. coli.…
Ver producto