Rat Nuclear receptor subfamily 1 group I member 2 (NR1I2) ELISA Kit

Este producto es parte de NR1I2-NR1I3 - -nuclear receptor subfamily 1 group I member
Rat Nuclear receptor subfamily 1 group I member 2 (NR1I2) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

687.5€ (96 tests)

Elisa Kits NR1I2

proveedor

Abbexa

reference

abx514996

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat Nuclear receptor subfamily 1 group I member 2 (NR1I2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Nuclear receptor subfamily 1 group I member 2 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

Nuclear receptor subfamily 1 group I member 2 (NR1I2), also known as the pregnane X receptor (PXR), is a nuclear receptor that regulates the expression of genes involved in drug metabolism, xenobiotic detoxification, and the transport of various substances PXR is activated by a wide range of compounds, including steroids, bile acids, and pharmaceuticals, and it controls the transcription of genes involved in the metabolism and clearance of these substances It is primarily expressed in the liver, intestine, and kidneys, where it helps protect the body from harmful substances by promoting their elimination PXR also regulates the expression of genes involved in bile acid metabolism, lipid homeostasis, and steroid hormone synthesis Dysregulation of PXR has been associated with drug resistance, liver diseases, and conditions related to altered drug metabolism Its role in detoxification and drug metabolism makes PXR a key target in pharmacology, particularly in managing drug interactions and toxicity

Características del producto

category

ELISA Kits


immunogen target

Nuclear receptor subfamily 1 group I member 2 (NR1I2)


reactivity

Rat


test range

0.312 ng/ml - 20 ng/ml


sensitivity

0.096 ng/ml


assay type

Sandwich


assay data

Quantitative


detection method

Colorimetric


sample type

Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


alias

BXR,PAR,PRR,PXR,SAR,SXR,ONR1,PAR1,PAR2,PARq,Orphan nuclear receptor PAR1,Orphan nuclear receptor PXR,Orphan nuclear receptor PAR1,Orphan nuclear receptor PXR,Pregnane X receptor


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

NR1I2


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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status

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