Rat Nuclear receptor subfamily 1 group I member 2 (NR1I2) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits NR1I2
proveedor
Abbexareference
abx514996Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Nuclear receptor subfamily 1 group I member 2 (NR1I2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Nuclear receptor subfamily 1 group I member 2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Nuclear receptor subfamily 1 group I member 2 (NR1I2), also known as the pregnane X receptor (PXR), is a nuclear receptor that regulates the expression of genes involved in drug metabolism, xenobiotic detoxification, and the transport of various substances PXR is activated by a wide range of compounds, including steroids, bile acids, and pharmaceuticals, and it controls the transcription of genes involved in the metabolism and clearance of these substances It is primarily expressed in the liver, intestine, and kidneys, where it helps protect the body from harmful substances by promoting their elimination PXR also regulates the expression of genes involved in bile acid metabolism, lipid homeostasis, and steroid hormone synthesis Dysregulation of PXR has been associated with drug resistance, liver diseases, and conditions related to altered drug metabolism Its role in detoxification and drug metabolism makes PXR a key target in pharmacology, particularly in managing drug interactions and toxicity
Características del producto
category
ELISA Kits
immunogen target
Nuclear receptor subfamily 1 group I member 2 (NR1I2)
reactivity
Rat
test range
0.312 ng/ml - 20 ng/ml
sensitivity
0.096 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
BXR,PAR,PRR,PXR,SAR,SXR,ONR1,PAR1,PAR2,PARq,Orphan nuclear receptor PAR1,Orphan nuclear receptor PXR,Orphan nuclear receptor PAR1,Orphan nuclear receptor PXR,Pregnane X receptor
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
NR1I2
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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