NR1I2 belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. This protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin.
Primary Antibodies
Polyclonal
Human
Nuclear Receptor Subfamily 1 Group I Member 2 (NR1I2)
Rabbit
Unconjugated
Liquid
ELISA, WB, IHC, IF/ICC, FCM
Purified through a protein A column, followed by peptide affinity purification.
PBS containing 0.09% sodium azide.
80 µl
400 µl
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
NR1I2
No
Shipped within 5-10 working days.
BXR,PAR,PRR,PXR,SAR,SXR,ONR1,PAR1,PAR2,PARq,Orphan nuclear receptor PAR1,Orphan nuclear receptor PXR,Orphan nuclear receptor PAR1,Orphan nuclear receptor PXR,Pregnane X receptor
This product is for research use only.
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Ver másNR1I2 Antibody is a Rabbit Polyclonal antibody against NR1I2. This gene product belongs to the nuclear receptor superfam...
175€ (20 µl)
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