Rat Neurotensin Receptor 1, High Affinity (NTSR1) ELISA Kit

Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for NTSR1
proveedor
Abbexareference
abx536080Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Neurotensin Receptor 1, High Affinity (NTSR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Neurotensin receptor type 1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
NTSR1 is a G protein-coupled receptor that binds neurotensin (NT), a neuropeptide involved in modulating neurotransmission, inflammation, and cell proliferation. NTSR1 is highly expressed in the central nervous system (CNS), particularly in the hypothalamus, midbrain, and limbic structures, where it regulates dopamine signaling, thermoregulation, and nociception. NTSR1 couples to Gq/11 proteins, activating phospholipase C (PLC), increasing intracellular calcium, and stimulating downstream pathways like MAPK and PI3K/Akt. In the periphery, NTSR1 is expressed in the gastrointestinal tract and immune cells, where it regulates gut motility, inflammation, and pain perception. Dysregulation of NTSR1 signaling is associated with neurological disorders, schizophrenia, cancer progression, and chronic pain. NTSR1 agonists are being explored for their neuroprotective and analgesic effects, while NTSR1 antagonists are being investigated for treating cancer due to the receptor’s role in promoting tumor cell proliferation and survival.
Características del producto
category
ELISA Kits
immunogen target
Neurotensin Receptor 1, High Affinity (NTSR1)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
NTSR1,NTR,NTR1,NTRH,neurotensin receptor type 1, Levocabastin-insensitive neurotensin receptor,NT-1R,neurotensin receptor 1 (high affinity)
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
NTSR1
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Quizá le pueda interesar
Neurotensin Receptor 1, High Affinity (NTSR1) Antibody

proveedor
Abbexareference
abx002203Tested Applications
WBreactivity
Human, Mousestatus
RUOclonality
PolyclonalNTSR1 Antibody is a Rabbit Polyclonal antibody against NTSR1. Neurotensin receptor 1 belongs to the large superfamily of...
312€ (60 µl)
Ver másHuman Neurotensin Receptor 1, High Affinity (NTSR1) ELISA Kit

proveedor
Abbexareference
abx152562Tested Applications
ELISAreactivity
Humanstatus
RUOHuman Neurotensin Receptor 1, High Affinity (NTSR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement ...
715€ (96 tests)
Ver másMouse Neurotensin Receptor 1, High Affinity (NTSR1) ELISA Kit

proveedor
Abbexareference
abx154478Tested Applications
ELISAreactivity
Mousestatus
RUOMouse Neurotensin Receptor 1, High Affinity (NTSR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement ...
715€ (96 tests)
Ver más