Human Neurotensin Receptor 1, High Affinity (NTSR1) ELISA Kit

Name: Human Neurotensin Receptor 1, High Affinity (NTSR1) ELISA Kit
Brand: Abbexa
SKU: abx152562
Price: 715 EUR
Availability: OnlineOnly

Este producto es parte de NTSR - Neurotensin Receptor

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for NTSR1

proveedor

Abbexa

reference

abx152562

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Neurotensin Receptor 1, High Affinity (NTSR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Neurotensin Receptor 1, High Affinity (NTSR1) concentrations in tissue homogenates, cell lysates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Neurotensin Receptor 1, High Affinity (NTSR1)

Background

NTSR1 is a G protein-coupled receptor that binds neurotensin (NT), a neuropeptide involved in modulating neurotransmission, inflammation, and cell proliferation. NTSR1 is highly expressed in the central nervous system (CNS), particularly in the hypothalamus, midbrain, and limbic structures, where it regulates dopamine signaling, thermoregulation, and nociception. NTSR1 couples to Gq/11 proteins, activating phospholipase C (PLC), increasing intracellular calcium, and stimulating downstream pathways like MAPK and PI3K/Akt. In the periphery, NTSR1 is expressed in the gastrointestinal tract and immune cells, where it regulates gut motility, inflammation, and pain perception. Dysregulation of NTSR1 signaling is associated with neurological disorders, schizophrenia, cancer progression, and chronic pain. NTSR1 agonists are being explored for their neuroprotective and analgesic effects, while NTSR1 antagonists are being investigated for treating cancer due to the receptor’s role in promoting tumor cell proliferation and survival.

Características del producto

immunogen target

Neurotensin Receptor 1, High Affinity (NTSR1)

reactivity

Human

test range

0.156 ng/ml - 10 ng/ml

sensitivity

< 0.07 ng/ml

assay type

Sandwich

assay data

Quantitative

form

Lyophilized

detection method

Colorimetric

sample type

Tissue homogenates, cell lysates and other biological fluids.

size 1

96 tests

size 2

5 × 96 tests

size 3

10 × 96 tests

alias

NTSR1,NTR,NTR1,NTRH,neurotensin receptor type 1, Levocabastin-insensitive neurotensin receptor,NT-1R,neurotensin receptor 1 (high affinity)

storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

or code

NTSR1

dry ice

uniprot id

https://www.uniprot.org/uniprotkb/P30989

gene id

https://www.ncbi.nlm.nih.gov/gene/4923

note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

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Neurotensin Receptor 1, High Affinity (NTSR1) Antibody

proveedor

Abbexa

reference

abx002203

Tested Applications

reactivity

Human, Mouse

status

RUO

clonality

Polyclonal

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