Rat Neuropeptide Y Receptor Y5 (NPY5R) Protein
208€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Rat Neuropeptide Y Receptor Y5 (NPY5R) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx654542
tested applications
WB, SDS-PAGE
Description
Rat Neuropeptide Y Receptor Y5 (NPY5R) Protein is a recombinant Rat protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Neuropeptide Y Receptor Y5 (NPY5R) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Please enquire. Tag: N-terminal His tag |
| Origin | Rat |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| Alias | NPY5R,NPY5-R,NPYY5-R,ood intake receptor,neuropeptide Y receptor type 5 |
| Background | Protein NPY5R |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
NPY5R is a G protein-coupled receptor that binds neuropeptide Y (NPY), peptide YY (PYY), and pancreatic polypeptide (PP). It is primarily expressed in the hypothalamus and limbic system, where it regulates appetite, energy homeostasis, and stress responses. NPY5R couples to Gi/o proteins, inhibiting adenylate cyclase and reducing cAMP levels, leading to modulation of neuronal signaling and feeding behavior. Activation of NPY5R promotes appetite stimulation and energy storage, playing a critical role in obesity and metabolic disorders. NPY5R also contributes to stress-related behaviors, anxiety, and cardiovascular regulation. Dysregulation of NPY5R signaling is associated with hyperphagia, obesity, and mood disorders. NPY5R antagonists are being explored as therapeutic agents to suppress appetite and reduce body weight in obesity. Its involvement in feeding behavior, stress regulation, and energy balance highlights NPY5R as a potential target for treating obesity, metabolic syndrome, and related mood disorders.
Related Products
Human NPYR5 (Neuropeptide Y Receptor Y5) ELISA Kit
Ver Producto
Human Neuropeptide Y Receptor Y5 (NPY5R) ELISA Kit
Human Neuropeptide Y Receptor Y5 (NPY5R) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human NPY5R concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of NPY5R
Ver Producto
Mouse Neuropeptide Y Receptor Y5 (NPY5R) ELISA Kit
Mouse Neuropeptide Y Receptor Y5 (NPY5R) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse NPY5R concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of NPY5R
Ver Producto