Human Neuropeptide Y Receptor Y5 (NPY5R) ELISA Kit

Name: Human Neuropeptide Y Receptor Y5 (NPY5R) ELISA Kit
Brand: Abbexa
SKU: abx152552
Price: 715 EUR
Availability: OnlineOnly

Este producto es parte de NPY - Neuropeptide Y Receptor

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for NPY5R

proveedor

Abbexa

reference

abx152552

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Neuropeptide Y Receptor Y5 (NPY5R) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human NPY5R concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of NPY5R

Background

NPY5R is a G protein-coupled receptor that binds neuropeptide Y (NPY), peptide YY (PYY), and pancreatic polypeptide (PP). It is primarily expressed in the hypothalamus and limbic system, where it regulates appetite, energy homeostasis, and stress responses. NPY5R couples to Gi/o proteins, inhibiting adenylate cyclase and reducing cAMP levels, leading to modulation of neuronal signaling and feeding behavior. Activation of NPY5R promotes appetite stimulation and energy storage, playing a critical role in obesity and metabolic disorders. NPY5R also contributes to stress-related behaviors, anxiety, and cardiovascular regulation. Dysregulation of NPY5R signaling is associated with hyperphagia, obesity, and mood disorders. NPY5R antagonists are being explored as therapeutic agents to suppress appetite and reduce body weight in obesity. Its involvement in feeding behavior, stress regulation, and energy balance highlights NPY5R as a potential target for treating obesity, metabolic syndrome, and related mood disorders.

Características del producto

immunogen target

Neuropeptide Y Receptor Y5 (NPY5R)

reactivity

Human

test range

0.312 ng/ml - 20 ng/ml

sensitivity

< 0.11 ng/ml

assay type

Sandwich

assay data

Quantitative

form

Lyophilized

detection method

Colorimetric

sample type

Tissue homogenates and other biological fluids.

size 1

96 tests

size 2

5 × 96 tests

size 3

10 × 96 tests

alias

NPY5R,NPY5-R,NPYY5-R,ood intake receptor,neuropeptide Y receptor type 5

storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

or code

NPY5R

dry ice

uniprot id

https://www.uniprot.org/uniprotkb/Q15761

gene id

https://www.ncbi.nlm.nih.gov/gene/4889

NCBI accession

NP_006165.1

note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

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proveedor

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reference

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reactivity

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status

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