Rat Netrin Receptor UNC5B (UNC5B) Protein
1079€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Rat Netrin Receptor UNC5B (UNC5B) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx691027
tested applications
SDS-PAGE
Description
Rat UNC5B Protein is a recombinant protein from Rat produced in HEK293 Cells. A DNA sequence encoding the rat UNC5B (NP_071543.1) (Met1-Asp373) was expressed with the Fc region of human IgG1 at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | UNC5B |
| Host | HEK293 cells |
| Origin | Rat |
| Observed MW | Molecular Weight: 65.7 kDa Sequence Fragment: Met1-Asp373 Tag: C-terminal Fc tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 85% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NP_071543.1 |
| Alias | UNC5H2,p53RDL1,Protein unc-5 homolog 2,Protein unc-5 homolog B,p53-regulated receptor for death and life protein 1,Netrin receptor UNC5B |
| Background | Protein UNC5B |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
unc-5 netrin receptor B (UNC5B) acts as a receptor for netrin-1, orchestrating key cellular processes like axonal guidance and vascular development. UNC5B ensures proper vascular and neuronal organization by transmitting repellent cues that direct cellular movements. In endothelial cells, UNC5B is vital for angiogenesis, controlling endothelial migration and sprouting. Beyond developmental contexts, UNC5B is implicated in tumor suppression through apoptosis activation in netrin-1’s absence, akin to its role as a dependence receptor. Dysregulation of UNC5B has been linked to pathological angiogenesis and malignancies, highlighting its dual importance in both developmental and pathological processes.
Related Products
Human UNC5B(Netrin Receptor UNC5B) ELISA Kit
Ver Producto
Human Netrin receptor UNC5B (UNC5B) ELISA Kit
Human Netrin receptor UNC5B (UNC5B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Netrin receptor UNC5B (UNC5B) concentrations in serum, plasma and other biological fluids.
Ver Producto
Netrin receptor UNC5B (UNC5B) Antibody
UNC5B Antibody is a Rabbit Polyclonal against UNC5B.
Ver Producto