Netrin receptor UNC5B (UNC5B) Antibody
169€ (20 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Netrin receptor UNC5B (UNC5B) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx334202
Tested Applications
ELISA, IHC, IF/ICC
Description
UNC5B Antibody is a Rabbit Polyclonal against UNC5B.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Netrin receptor UNC5B (UNC5B) Immunogen: Recombinant Human Netrin receptor UNC5B protein (404-517AA). |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/200 - 1/500, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8IZJ1 |
| Gene ID | 219699 |
| Alias | UNC5H2,p53RDL1,Protein unc-5 homolog 2,Protein unc-5 homolog B,p53-regulated receptor for death and life protein 1,Netrin receptor UNC5B |
| Background | Antibody anti-UNC5B |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
unc-5 netrin receptor B (UNC5B) acts as a receptor for netrin-1, orchestrating key cellular processes like axonal guidance and vascular development. UNC5B ensures proper vascular and neuronal organization by transmitting repellent cues that direct cellular movements. In endothelial cells, UNC5B is vital for angiogenesis, controlling endothelial migration and sprouting. Beyond developmental contexts, UNC5B is implicated in tumor suppression through apoptosis activation in netrin-1’s absence, akin to its role as a dependence receptor. Dysregulation of UNC5B has been linked to pathological angiogenesis and malignancies, highlighting its dual importance in both developmental and pathological processes.
Productos relacionados
Human Netrin receptor UNC5B (UNC5B) ELISA Kit
Human Netrin receptor UNC5B (UNC5B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Netrin …
Ver producto Netrin receptor UNC5B (UNC5B) Antibody
UNC5B Antibody is a Rabbit Polyclonal against UNC5B.…
Ver producto Netrin receptor UNC5B (UNC5B) Antibody (HRP)
UNC5B Antibody (HRP) is a Rabbit Polyclonal against UNC5B.…
Ver producto