Rat Netrin receptor UNC5B (UNC5B) Protein
234€ (2 µg)
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name
Rat Netrin receptor UNC5B (UNC5B) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx680576
Description
Rat Netrin receptor UNC5B (UNC5B) Protein is a recombinant protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Netrin receptor UNC5B (UNC5B) |
| Origin | Rat |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Size 1 | 2 µg |
| Size 2 | 10 µg |
| Size 3 | 1 mg |
| Form | |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| Alias | UNC5H2,p53RDL1,Protein unc-5 homolog 2,Protein unc-5 homolog B,p53-regulated receptor for death and life protein 1,Netrin receptor UNC5B |
| Background | Protein UNC5B |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
unc-5 netrin receptor B (UNC5B) acts as a receptor for netrin-1, orchestrating key cellular processes like axonal guidance and vascular development. UNC5B ensures proper vascular and neuronal organization by transmitting repellent cues that direct cellular movements. In endothelial cells, UNC5B is vital for angiogenesis, controlling endothelial migration and sprouting. Beyond developmental contexts, UNC5B is implicated in tumor suppression through apoptosis activation in netrin-1’s absence, akin to its role as a dependence receptor. Dysregulation of UNC5B has been linked to pathological angiogenesis and malignancies, highlighting its dual importance in both developmental and pathological processes.
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