Rat Netrin receptor UNC5B (UNC5B) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits UNC5B
proveedor
Abbexareference
abx552624Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Netrin receptor UNC5B (UNC5B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Netrin receptor UNC5B (UNC5B) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
unc-5 netrin receptor B (UNC5B) acts as a receptor for netrin-1, orchestrating key cellular processes like axonal guidance and vascular development. UNC5B ensures proper vascular and neuronal organization by transmitting repellent cues that direct cellular movements. In endothelial cells, UNC5B is vital for angiogenesis, controlling endothelial migration and sprouting. Beyond developmental contexts, UNC5B is implicated in tumor suppression through apoptosis activation in netrin-1’s absence, akin to its role as a dependence receptor. Dysregulation of UNC5B has been linked to pathological angiogenesis and malignancies, highlighting its dual importance in both developmental and pathological processes.
Características del producto
category
ELISA Kits
immunogen target
Netrin receptor UNC5B (UNC5B)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
UNC5H2,p53RDL1,Protein unc-5 homolog 2,Protein unc-5 homolog B,p53-regulated receptor for death and life protein 1,Netrin receptor UNC5B
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
UNC5B
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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