Rat Meteorin (METRN) Protein

247€ (10 µg)
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name
Rat Meteorin (METRN) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167757
tested applications
WB, SDS-PAGE
Description
Meteorin Protein is a recombinant Rat protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Meteorin (METRN) |
Host | E. coli |
Origin | Rat |
Conjugation | Unconjugated |
Observed MW | Molecular Weight: Calculated MW: 33.0 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Gly22-Asp291 Tag: N-terminal His tag |
Expression | Recombinant |
Purity | > 95% |
Size 1 | 10 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 500 µg |
Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
Tested Applications | WB, SDS-PAGE |
Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
Availability | Shipped within 5-7 working days. |
Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Alias | glial cell differentiation regulator,C16orf23,c380A1.2 |
Background | Protein METRN |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Meteorin, encoded by the METRN gene, is a secreted protein primarily involved in neural and glial cell differentiation and regeneration. METRN is expressed in the nervous system and functions as a neurotrophic factor, promoting neurite outgrowth and supporting the survival of glial progenitor cells. It is also implicated in modulating inflammatory responses in the central nervous system (CNS), playing a protective role in neurodegenerative diseases and brain injuries. Meteorin activates the Jak/STAT and PI3K/Akt signaling pathways to exert its biological effects, including promoting astrocyte differentiation and maintaining the blood-brain barrier's integrity. Emerging studies suggest that METRN may also have a role in muscle regeneration and metabolic regulation, expanding its functional repertoire beyond the CNS.
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