Meteorin (METRN) Antibody
299€ (100 µl)
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935106861
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name
Meteorin (METRN) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx130105
tested applications
WB, IHC, IF/ICC
Description
Meteorin Antibody is a Rabbit Polyclonal antibody against C-Ros Oncogene 1, Receptor Tyrosine Kinase.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Meteorin (METRN) |
| Host | Rabbit |
| Reactivity | Rat |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q5Q0T9 |
| Alias | glial cell differentiation regulator,C16orf23,c380A1.2 |
| Background | Antibody anti-METRN |
| Status | RUO |
Descripción
Meteorin, encoded by the METRN gene, is a secreted protein primarily involved in neural and glial cell differentiation and regeneration. METRN is expressed in the nervous system and functions as a neurotrophic factor, promoting neurite outgrowth and supporting the survival of glial progenitor cells. It is also implicated in modulating inflammatory responses in the central nervous system (CNS), playing a protective role in neurodegenerative diseases and brain injuries. Meteorin activates the Jak/STAT and PI3K/Akt signaling pathways to exert its biological effects, including promoting astrocyte differentiation and maintaining the blood-brain barrier's integrity. Emerging studies suggest that METRN may also have a role in muscle regeneration and metabolic regulation, expanding its functional repertoire beyond the CNS.
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