Meteorin (METRN) Antibody

Este producto es parte de METRN - Meteorin (Like)
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286€ (100 µl)

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935106861
info@markelab.com
name
Meteorin (METRN) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx129444
tested applications
WB, IHC

Description

Meteorin Antibody is a Rabbit Polyclonal antibody against Meteorin.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Target: Meteorin (METRN)
Immunogen: abx168390 - Recombinant METRN (Gly22-Asp291) expressed in E. coli
Host
Rabbit
Reactivity
Mouse
Recommended Dilution
WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
Size 1
100 µl
Size 2
200 µl
Size 3
1 ml
Form
Liquid
Tested Applications
WB, IHC
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-7 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q8C1Q4
Alias
glial cell differentiation regulator,C16orf23,c380A1.2
Background
Antibody anti-METRN
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

Meteorin, encoded by the METRN gene, is a secreted protein primarily involved in neural and glial cell differentiation and regeneration. METRN is expressed in the nervous system and functions as a neurotrophic factor, promoting neurite outgrowth and supporting the survival of glial progenitor cells. It is also implicated in modulating inflammatory responses in the central nervous system (CNS), playing a protective role in neurodegenerative diseases and brain injuries. Meteorin activates the Jak/STAT and PI3K/Akt signaling pathways to exert its biological effects, including promoting astrocyte differentiation and maintaining the blood-brain barrier's integrity. Emerging studies suggest that METRN may also have a role in muscle regeneration and metabolic regulation, expanding its functional repertoire beyond the CNS.

Related Products

abx168390

Mouse Meteorin (METRN) Protein

Meteorin Protein is a recombinant Mouse protein expressed in E. coli.

Ver Producto