Rat Lysosome-associated membrane glycoprotein 5 (LAMP5) ELISA Kit

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Description
Rat Lysosome-associated membrane glycoprotein 5 (LAMP5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Lysosome-associated membrane glycoprotein 5 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Lysosome-associated membrane glycoprotein 5 (LAMP5) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q5PPI4 |
| Alias | BAD-LAMP,BADLAMP,C20orf103,LAMP-5,UNC-46,Brain and dendritic cell-associated LAMP,Brain-associated LAMP-like protein |
| Background | Elisa Kits for: LAMP5 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
Lysosome-associated membrane glycoprotein 5 (LAMP5) is a member of the LAMP family of lysosomal membrane proteins, primarily expressed in neuronal tissues and specific cell types such as inhibitory interneurons LAMP5 plays a key role in maintaining lysosomal function, particularly in neurons, where it regulates endosomal-lysosomal trafficking and protein degradation pathways It is involved in synaptic transmission and neuronal homeostasis, contributing to proper neuronal development and function Dysregulation of LAMP5 expression has been associated with neurodevelopmental disorders and neurodegenerative diseases such as Alzheimer’s disease and epilepsy, where impaired lysosomal activity leads to neuronal dysfunction LAMP5 also plays a role in autophagy and cellular stress responses, where it regulates lysosomal biogenesis and fusion processes Recent studies have highlighted its potential involvement in tumorigenesis, particularly in brain cancers, where it can influence lysosome-mediated processes critical for tumor progression and survival
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