Mouse Lysosome-associated membrane glycoprotein 5 (LAMP5) ELISA Kit

Este producto es parte de LAMP- Lysosomal Associated Membrane Protein
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Lysosome-associated membrane glycoprotein 5 (LAMP5) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx530674
tested applications
ELISA

Description

Mouse Lysosome-associated membrane glycoprotein 5 (LAMP5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Lysosome-associated membrane glycoprotein 5 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Lysosome-associated membrane glycoprotein 5 (LAMP5)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q9D387
Gene ID
76161
Alias
BAD-LAMP,BADLAMP,C20orf103,LAMP-5,UNC-46,Brain and dendritic cell-associated LAMP,Brain-associated LAMP-like protein
Background
Elisa kits for LAMP5
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Lysosome-associated membrane glycoprotein 5 (LAMP5) is a member of the LAMP family of lysosomal membrane proteins, primarily expressed in neuronal tissues and specific cell types such as inhibitory interneurons LAMP5 plays a key role in maintaining lysosomal function, particularly in neurons, where it regulates endosomal-lysosomal trafficking and protein degradation pathways It is involved in synaptic transmission and neuronal homeostasis, contributing to proper neuronal development and function Dysregulation of LAMP5 expression has been associated with neurodevelopmental disorders and neurodegenerative diseases such as Alzheimer’s disease and epilepsy, where impaired lysosomal activity leads to neuronal dysfunction LAMP5 also plays a role in autophagy and cellular stress responses, where it regulates lysosomal biogenesis and fusion processes Recent studies have highlighted its potential involvement in tumorigenesis, particularly in brain cancers, where it can influence lysosome-mediated processes critical for tumor progression and survival

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