Mouse Lysosome-associated membrane glycoprotein 5 (LAMP5) ELISA Kit

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Description
Mouse Lysosome-associated membrane glycoprotein 5 (LAMP5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Lysosome-associated membrane glycoprotein 5 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
Category | ELISA Kits |
Immunogen Target | Lysosome-associated membrane glycoprotein 5 (LAMP5) |
Reactivity | Mouse |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Test Range | 0.156 ng/ml - 10 ng/ml |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Form | Lyophilized |
Tested Applications | ELISA |
Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
UniProt ID | Q9D387 |
Gene ID | 76161 |
Alias | BAD-LAMP,BADLAMP,C20orf103,LAMP-5,UNC-46,Brain and dendritic cell-associated LAMP,Brain-associated LAMP-like protein |
Background | Elisa kits for LAMP5 |
Status | RUO |
Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Lysosome-associated membrane glycoprotein 5 (LAMP5) is a member of the LAMP family of lysosomal membrane proteins, primarily expressed in neuronal tissues and specific cell types such as inhibitory interneurons LAMP5 plays a key role in maintaining lysosomal function, particularly in neurons, where it regulates endosomal-lysosomal trafficking and protein degradation pathways It is involved in synaptic transmission and neuronal homeostasis, contributing to proper neuronal development and function Dysregulation of LAMP5 expression has been associated with neurodevelopmental disorders and neurodegenerative diseases such as Alzheimer’s disease and epilepsy, where impaired lysosomal activity leads to neuronal dysfunction LAMP5 also plays a role in autophagy and cellular stress responses, where it regulates lysosomal biogenesis and fusion processes Recent studies have highlighted its potential involvement in tumorigenesis, particularly in brain cancers, where it can influence lysosome-mediated processes critical for tumor progression and survival
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