Rat Lysophosphatidic acid receptor 6 (LPAR6) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for LPAR6
proveedor
Abbexareference
abx531259Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Lysophosphatidic acid receptor 6 (LPAR6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Lysophosphatidic acid receptor 6 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
LPAR6, also known as P2Y5, is a G protein-coupled receptor activated by lysophosphatidic acid (LPA). It primarily couples to G12/13 proteins and plays a key role in cellular signaling related to cytoskeletal reorganization, cell migration, and proliferation. LPAR6 is predominantly expressed in hair follicles, skin, and epithelial tissues, where it regulates hair growth and skin homeostasis. Mutations in LPAR6 are associated with inherited hair disorders such as hypotrichosis and woolly hair syndrome, where impaired LPA signaling disrupts normal hair follicle function. Beyond its role in hair biology, LPAR6 contributes to epithelial cell survival and wound healing processes. LPAR6 has also been linked to cancer progression, particularly in promoting cell migration, metastasis, and resistance to apoptosis in epithelial cancers. Dysregulation of LPAR6 signaling has implications in skin disorders, inflammatory conditions, and tumor progression. LPAR6 represents a therapeutic target for managing hair growth disorders, epithelial repair, and cancer metastasis.
Características del producto
category
ELISA Kits
immunogen target
Lysophosphatidic acid receptor 6 (LPAR6)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
LPAR6,ARWH1,HYPT8,LAH3,LPA-6,P2RY5,P2Y5,LPA receptor 6,oleoyl-L-alpha-lysophosphatidic acid receptor,P2Y purinoceptor 5,purinergic receptor 5
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
LPAR6
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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