Rat KH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 2 (KHDRBS2) ELISA Kit

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Rat KH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 2 (KHDRBS2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat KH domain-containing, RNA-binding, signal transduction-associated protein 2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
Category | ELISA Kits |
Immunogen Target | KH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 2 (KHDRBS2) |
Reactivity | Rat |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Test Range | 0.156 ng/ml - 10 ng/ml |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Form | Lyophilized |
Tested Applications | ELISA |
Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
UniProt ID | Q920F3 |
Alias | KHDRBS2-OT, KHDRBS2-OT1, SLM-1, SLM1,Sam68-like mammalian protein 1 |
Background | Elisa kits for KHDRBS2 |
Status | RUO |
Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
KHDRBS2, also called SLIM-1 (Sam68-like mammalian protein 1), is a KH-domain-containing RNA-binding protein that regulates RNA splicing, transport, and translation. It functions downstream of receptor tyrosine kinases and cytoplasmic signaling pathways, linking RNA metabolism to cell signaling. KHDRBS2 is expressed predominantly in differentiated tissues, including the brain, where it regulates alternative splicing and mRNA stability of genes involved in neuronal differentiation, synaptic function, and cellular adhesion. It interacts with SH2-containing signaling proteins and participates in regulating processes like cellular differentiation and tissue-specific gene expression. Dysregulation of KHDRBS2 contributes to neurological disorders and has been implicated in tumor suppression by modulating growth-related mRNAs. Knockout models suggest its role in neuronal development and maintaining cellular homeostasis through mRNA regulation.
Related Products

KH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 2 (KHDRBS2) Antibody
KHDRBS2 Antibody is a Rabbit Polyclonal Antibody against KHDRBS2.
Ver Producto
KH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 2 (KHDRBS2) Antibody
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis. Binds both poly (A) and poly (U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity).
Ver Producto
KH Domain-Containing, RNA-Binding, Signal Transduction-Associated Protein 2 (KHDRBS2) Antibody
KHDRBS2 Antibody is a Mouse Monoclonal against KHDRBS2.
Ver Producto