Rat Interleukin 4 (IL4) Protein
416€ (20 µg)
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935106861
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name
Rat Interleukin 4 (IL4) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx694297
tested applications
SDS-PAGE
Description
Rat Interleukin 4 (IL4) Protein is a recombinant Rat protein expressed in HEK293 cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Host | HEK293 cells |
| Origin | Rat |
| Observed MW | Molecular Weight: Calculated MW: 16.5 kDa Observed MW (SDS-PAGE): 17 kDa Sequence Fragment: Met1-Ser147 Tag: C-terminal His tag |
| Expression | Recombinant |
| Purity | >90% (SDS-PAGE) |
| Size 1 | 20 µg |
| Size 2 | 100 µg |
| Form | Lyophilized Reconstitute in sterile H2O. Do not vortex. |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, 5% Trehalose, 5% Mannitol, 0.01% Tween-80. |
| Availability | Shipped within 5-15 working days. |
| Storage | Store lyophilized between -20 °C and -80 °C. |
| Dry Ice | No |
| UniProt ID | P20096 |
| Gene ID | 287287 |
| NCBI Accession | NP_958427.1 |
| Alias | BSF1,IL-4,BCGF1,BSF-1,BCGF-1,B-cell stimulatory factor 1,Binetrakin,Lymphocyte stimulatory factor 1,Pitrakinra |
| Background | Protein IL4 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Interleukin-4 (IL4) is a crucial cytokine in the immune system, primarily involved in the regulation of humoral (antibody-mediated) immune responses and the differentiation of immune cells. It is produced by several immune cells, including activated CD4+ T cells (specifically Th2 cells), mast cells, basophils, eosinophils, and, to a lesser extent, CD8+ T cells. IL-4 is a member of the interleukin family of cytokines and plays a key role in driving the differentiation of naïve helper T cells (Th0) into Th2 cells, which are central to the adaptive immune response. This cytokine is also vital in inducing B cell class switching to immunoglobulin E (IgE), a process essential for allergic reactions. In addition to its immune-regulatory functions, IL-4 is heavily involved in allergic diseases such as asthma, allergic rhinitis, and atopic dermatitis. IL-4 mediates a wide range of biological effects that contribute to inflammation, allergy, and immune system modulation.
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