Rat Interleukin 31 (IL31) Protein
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935106861
info@markelab.com
Precio
247€ (10 µg)
Protein IL31
proveedor
Abbexareference
abx067521Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Rat Interleukin 31 (IL31) is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).
Background
Interleukin 31 (IL31) is a cytokine belonging to the IL-6 cytokine family that plays a central role in the regulation of immune responses and is heavily implicated in inflammatory processes, particularly in chronic pruritic (itching) skin disorders. IL-31 is primarily produced by activated T helper 2 (Th2) cells, a subset of T cells involved in allergic responses and the regulation of immune responses to extracellular pathogens. IL-31 was discovered as a cytokine that can link the immune system with the nervous system, particularly in the skin, where it triggers pruritus and inflammatory responses. The IL-31 receptor is widely expressed, being found on keratinocytes, fibroblasts, epithelial cells, and immune cells, which suggests its involvement in skin and tissue homeostasis
Características del producto
category
Proteins and Peptides
origin
Rat
host
E. coli
immunogen target
Interleukin 31 (IL31)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 45.9 kDa Observed MW (SDS-PAGE): 46 kDa Concentration: Prior to lyophilization: 150 µg/ml Sequence Fragment: Cys55-Glu183 Tag: N-terminal His tag and GST tag
expression
Recombinant
purity
> 97%
buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
IL31
dry ice
No
availability
Shipped within 5-12 working days.
alias
IL-31
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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