Rat Growth Differentiation Factor 15 (GDF15) Protein
Pida mas información
935106861
info@markelab.com
Precio
237.5€ (10 µg)
Protein GDF15
proveedor
Abbexareference
abx066942Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Rat Growth Differentiation Factor 15 (GDF15) Protein is a recombinant Rat protein produced in E. coli using Prokaryotic expression. This protein is the immunogen for the following antibodies: abx103433
Background
GDF15, a stress-responsive cytokine, stands as a distinct member within the diverse TGF-β superfamily. Its expression is typically low in most tissues during normal physiological conditions. However, when cardiac myocytes face ischemia or heightened ventricular wall stress, GDF-15 expression intensifies significantly. This cytokine has emerged as a potent prognostic indicator in various diseases, including heart diseases and cancer. Interestingly, it appears to act protectively against cardiac injury, attributed to its antihypertrophic, antiapoptotic, and anti-inflammatory properties, although the specific receptor through which GDF-15 exerts its effects remains unidentified. Studies have revealed a positive correlation between elevated GDF-15 levels and factors such as LV mass, IL-6, and MMP-9 levels in patients with heart failure (HF)
Características del producto
category
Proteins and Peptides
origin
Rat
host
E. coli
immunogen target
Growth Differentiation Factor 15 (GDF15)
host
E. coli
conjugation
Unconjugated
form
Lyophilized
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
expression
Recombinant
purity
> 97%
buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
GDF15
dry ice
No
availability
Shipped within 5-7 working days.
alias
HG,PDF,MIC1;,PLAB,MIC-1,NAG-1,PTGFB, GDF-15
uniprot id
note
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
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