Rat Growth Differentiation Factor 15 (GDF15) Protein

Este producto es parte de GDF15 - Growth Differentiation Factor 15
Rat Growth Differentiation Factor 15 (GDF15) Protein

Pida mas información

935106861

info@markelab.com

Precio

237.5€ (10 µg)

Protein GDF15

proveedor

Abbexa

reference

abx066942

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Rat Growth Differentiation Factor 15 (GDF15) Protein is a recombinant Rat protein produced in E. coli using Prokaryotic expression. This protein is the immunogen for the following antibodies: abx103433


Background

GDF15, a stress-responsive cytokine, stands as a distinct member within the diverse TGF-β superfamily. Its expression is typically low in most tissues during normal physiological conditions. However, when cardiac myocytes face ischemia or heightened ventricular wall stress, GDF-15 expression intensifies significantly. This cytokine has emerged as a potent prognostic indicator in various diseases, including heart diseases and cancer. Interestingly, it appears to act protectively against cardiac injury, attributed to its antihypertrophic, antiapoptotic, and anti-inflammatory properties, although the specific receptor through which GDF-15 exerts its effects remains unidentified. Studies have revealed a positive correlation between elevated GDF-15 levels and factors such as LV mass, IL-6, and MMP-9 levels in patients with heart failure (HF)

Características del producto

category

Proteins and Peptides


origin

Rat


host

E. coli


immunogen target

Growth Differentiation Factor 15 (GDF15)


host

E. coli


conjugation

Unconjugated


form

Lyophilized


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

1 mg


expression

Recombinant


purity

> 97%


buffer

Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

GDF15


dry ice

No


availability

Shipped within 5-7 working days.


alias

HG,PDF,MIC1;,PLAB,MIC-1,NAG-1,PTGFB, GDF-15


note

This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.


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