Rat G-Protein Coupled Receptor 119 (GPR119) ELISA Kit
715€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Rat G-Protein Coupled Receptor 119 (GPR119) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx525794
tested applications
ELISA
Description
Rat G-Protein Coupled Receptor 119 (GPR119) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Glucose-dependent insulinotropic receptor concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | G-Protein Coupled Receptor 119 (GPR119) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q7TQN8 |
| Alias | GPR119,GPCR2,glucose-dependent insulinotropic receptor,G-protein coupled receptor 2,G protein-coupled receptor 119 |
| Background | Elisa kits for GPR119 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
GPR119 is a G protein-coupled receptor primarily expressed in pancreatic β-cells and enteroendocrine cells in the gastrointestinal tract. It is activated by endogenous lipids such as oleoylethanolamide (OEA) and dietary-derived fatty acid derivatives. GPR119 plays a critical role in glucose homeostasis and energy metabolism by stimulating glucose-dependent insulin secretion from pancreatic β-cells and promoting the release of incretin hormones like glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) from intestinal cells. This dual action improves insulin sensitivity and regulates appetite, making GPR119 an attractive therapeutic target for type 2 diabetes and obesity. Activation of GPR119 leads to cAMP accumulation and downstream activation of insulinotropic pathways, enhancing glucose control without causing hypoglycemia. Dysregulation of GPR119 signaling has been associated with metabolic disorders, including insulin resistance and obesity. GPR119 agonists are currently being developed to improve glycemic control and promote weight loss, highlighting its significance in metabolic health.
Related Products
G Protein-Coupled Receptor 119 (GPR119) Antibody
GPR119 Antibody is a Rabbit Polyclonal against GPR119.
Ver Producto
G-Protein Coupled Receptor 119 (GPR119) Antibody
GPR119 Antibody is a Goat Polyclonal antibody against GPR119.
Ver Producto
Human Glucose-dependent insulinotropic receptor (GPR119) ELISA Kit
Human Glucose-dependent insulinotropic receptor (GPR119) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Glucose-dependent insulinotropic receptor (GPR119) concentrations in tissue homogenates, cell lysates and other biological fluids.
Ver Producto