Rat Early Activation Antigen CD69 (CD69) Protein

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935106861
info@markelab.com
Precio
247€ (10 µg)
Protein CD69
proveedor
Abbexareference
abx066167Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Rat C-Type Lectin Domain Family 2, Member C (CLEC2C) is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).
Background
CD69, also known as activation inducer molecule (AIM), is a type II transmembrane glycoprotein expressed primarily on the surface of activated immune cells, including T cells, B cells, natural killer (NK) cells, macrophages, and dendritic cells. CD69 is one of the earliest surface markers to be upregulated after lymphocyte activation, making it a widely used marker of immune cell activation. Its expression can be induced by a variety of stimuli, including antigen recognition, cytokines, and inflammatory signals. In addition to its role in immune activation, CD69 also plays critical roles in immune homeostasis, inflammation regulation, and tissue retention of lymphocytes. It functions as a key regulator of immune responses, particularly through its involvement in the migration and localization of immune cells to sites of inflammation or infection. Furthermore, CD69 is important in maintaining tissue-specific immunity in organs such as the lungs and intestines, where resident immune cells contribute to mucosal defense.
Características del producto
category
Proteins and Peptides
origin
Rat
host
E. coli
immunogen target
Early Activation Antigen CD69 (CD69)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 19.9 kDa Observed MW (SDS-PAGE): 20 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Cys43-Glu187 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
CD69
dry ice
No
availability
Shipped within 5-7 working days.
alias
AIM,EA1,MLR-3,CLEC2C,GP32/28,BL-AC/P26,Early activation antigen CD69,Activation inducer molecule,C-type lectin domain family 2 member C
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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