Early Activation Antigen CD69 (CD69) Antibody
195€ (20 µl)
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935106861
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name
Early Activation Antigen CD69 (CD69) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx001662
tested applications
ELISA, WB
Description
CD69 Antibody is a Rabbit Polyclonal antibody against CD69. This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. [provided by RefSeq, Aug 2011].
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Early Activation Antigen CD69 (CD69) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.09% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q07108 |
| Gene ID | 969 |
| NCBI Accession | NP_001772.1 |
| Alias | AIM,EA1,MLR-3,CLEC2C,GP32/28,BL-AC/P26,Early activation antigen CD69,Activation inducer molecule,C-type lectin domain family 2 member C |
| Background | Antibody anti-CD69 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
CD69, also known as activation inducer molecule (AIM), is a type II transmembrane glycoprotein expressed primarily on the surface of activated immune cells, including T cells, B cells, natural killer (NK) cells, macrophages, and dendritic cells. CD69 is one of the earliest surface markers to be upregulated after lymphocyte activation, making it a widely used marker of immune cell activation. Its expression can be induced by a variety of stimuli, including antigen recognition, cytokines, and inflammatory signals. In addition to its role in immune activation, CD69 also plays critical roles in immune homeostasis, inflammation regulation, and tissue retention of lymphocytes. It functions as a key regulator of immune responses, particularly through its involvement in the migration and localization of immune cells to sites of inflammation or infection. Furthermore, CD69 is important in maintaining tissue-specific immunity in organs such as the lungs and intestines, where resident immune cells contribute to mucosal defense.
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