Rat Coronin 1A (CORO1A) Protein
234€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Rat Coronin 1A (CORO1A) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167663
tested applications
WB, SDS-PAGE
Description
Coronin 1A Protein is a recombinant Rat protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Coronin 1A (CORO1A) |
| Host | E. coli |
| Origin | Rat |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 25.7 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met1-Glu204 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | p57,IMD8,TACO,CLABP,HCORO1,CLIPINA,CORO1,Tryptophan aspartate-containing coat protein (TACO),Coronin-like protein p57,Coronin-like protein A,Clipin-A,Coronin-1A |
| Background | Protein CORO1A |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Coronin 1A (CORO1A) is a member of the coronin family of proteins, which play key roles in regulating actin dynamics and cellular processes such as endocytosis, cytokinesis, and immune cell signaling. CORO1A, specifically, is crucial for the function of immune cells, including T cells and macrophages. It is involved in controlling actin polymerization and organization, which affects cell motility, phagocytosis, and intracellular trafficking. CORO1A has been implicated in the regulation of both the immune response and synaptic plasticity in neurons. Mutations or dysregulation of CORO1A can lead to impaired immune function, and it has been linked to immune disorders, highlighting its role in maintaining cellular integrity and function during immune responses.
Related Products
Human CORO1A (Coronin-1A) ELISA Kit
Ver Producto
CORO1A antibody
May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria-infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes.
Ver Producto