Human Coronin 1A (CORO1A) Protein
234€ (10 µg)
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name
Human Coronin 1A (CORO1A) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx066127
tested applications
WB, SDS-PAGE
Description
Human Coronin 1A (CORO1A) Protein is a recombinant Human protein produced in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Coronin 1A (CORO1A) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 25.1 kDa Observed MW (SDS-PAGE): 25 kDa Concentration: Prior to lyophilization: 250 µg/ml Sequence Fragment: Arg7-Glu204 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 10 mM PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in 10 mM PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P31146 |
| Alias | p57,IMD8,TACO,CLABP,HCORO1,CLIPINA,CORO1,Tryptophan aspartate-containing coat protein (TACO),Coronin-like protein p57,Coronin-like protein A,Clipin-A,Coronin-1A |
| Background | Protein CORO1A |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Coronin 1A (CORO1A) is a member of the coronin family of proteins, which play key roles in regulating actin dynamics and cellular processes such as endocytosis, cytokinesis, and immune cell signaling. CORO1A, specifically, is crucial for the function of immune cells, including T cells and macrophages. It is involved in controlling actin polymerization and organization, which affects cell motility, phagocytosis, and intracellular trafficking. CORO1A has been implicated in the regulation of both the immune response and synaptic plasticity in neurons. Mutations or dysregulation of CORO1A can lead to impaired immune function, and it has been linked to immune disorders, highlighting its role in maintaining cellular integrity and function during immune responses.
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