Rat Dendritic Cell Inhibitory Receptor 2 (CLEC4A2) Protein

Este producto es parte de CLEC4A - C-type lectin domain family 4 member A
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1235€ (100 µg)

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935106861
info@markelab.com
name
Rat Dendritic Cell Inhibitory Receptor 2 (CLEC4A2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx693422
tested applications
SDS-PAGE

Description

Dendritic Cell Inhibitory Receptor 2 (CLEC4A2) protein is a recombinant Rat protein expressed in HEK293 cells.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Dendritic Cell Inhibitory Receptor 2 (CLEC4A2)
Host
HEK293 cells
Assay Type
Activity: Not tested
Sequence Fragment: Gln70-Ser235
Tag: N-terminal His tag
Origin
Rat
Observed MW
21.8 kDa
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Size 1
100 µg
Form
Lyophilized
Tested Applications
SDS-PAGE
Buffer
Prior to lyophilization: Sterile PBS, pH 7.4.
Availability
Shipped within 5-15 working days.
Storage
Storage: Store lyophilized between -20 °C and -80°C.
Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months.
Shelf Life: 12 months.
Dry Ice
No
UniProt ID
Q5YIS1
Alias
DCIR,LLIR,CD367,DDB27,hDCIR,CLECSF6,HDCGC13P,C-type lectin DDB27,C-type lectin superfamily member 6,Dendritic cell immunoreceptor,Lectin-like immunoreceptor
Background
Protein CLEC4A
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Endotoxin Level: < 1.0 EU per µg (LAL method).

Descripción

CLEC4A (C-type lectin domain family 4 member A), also known as DCIR (dendritic cell immunoreceptor), is a receptor found on the surface of various immune cells, particularly dendritic cells (DCs) and monocytes. CLEC4A is part of the C-type lectin receptor (CLR) family, a group of proteins that play key roles in the immune system, especially in pathogen recognition, immune homeostasis, and inflammatory responses. As a member of this family, CLEC4A can recognize and bind to carbohydrate structures found on pathogens, self-antigens, and damaged cells. This binding facilitates immune responses and communication between cells of the immune system. CLEC4A has an important immunomodulatory role and is involved in both activating and inhibitory signaling pathways. Its ability to bind self-antigens and regulate immune responses is critical in maintaining immune tolerance, thus preventing autoimmune responses. Its expression in dendritic cells and other antigen-presenting cells highlights its relevance in adaptive immunity, where it influences T-cell activation and the shaping of immune responses. Additionally, CLEC4A is implicated in various autoimmune diseases and infections, making it an important target for therapeutic research.
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