Rat ATP Binding Cassette Transporter B8 (ABCB8) ELISA Kit

Este producto es parte de ABCB - ATP binding cassette subfamily B member
Rat ATP Binding Cassette Transporter B8 (ABCB8) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for ABCB8

proveedor

Abbexa

reference

abx500431

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat ATP Binding Cassette Transporter B8 (ABCB8) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat ATP-binding cassette sub-family B member 8, mitochondrial concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

ABCB8 is a mitochondrial ATP-binding cassette transporter involved in the export of iron-sulfur cluster intermediates and possibly other substrates from mitochondria to the cytosol. This function is critical for maintaining cellular iron homeostasis, facilitating the proper assembly of iron-sulfur cluster-containing proteins, and regulating oxidative stress. ABCB8 is highly expressed in metabolically active tissues, such as the heart, skeletal muscle, and liver, where mitochondrial function is crucial. Dysregulation of ABCB8 can lead to mitochondrial iron overload, contributing to oxidative damage and cellular dysfunction, particularly in cardiomyocytes. Emerging evidence suggests that ABCB8 plays a protective role in maintaining mitochondrial integrity under stress conditions, making it an important factor in cardiovascular health and mitochondrial-related diseases.

Características del producto

category

ELISA Kits


immunogen target

ATP Binding Cassette Transporter B8 (ABCB8)


reactivity

Rat


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

EST328128,M-ABC1,MABC1,MITOSUR


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

ABCB8


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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