Rat ATP Binding Cassette Transporter B8 (ABCB8) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ABCB8
proveedor
Abbexareference
abx500431Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat ATP Binding Cassette Transporter B8 (ABCB8) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat ATP-binding cassette sub-family B member 8, mitochondrial concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ABCB8 is a mitochondrial ATP-binding cassette transporter involved in the export of iron-sulfur cluster intermediates and possibly other substrates from mitochondria to the cytosol. This function is critical for maintaining cellular iron homeostasis, facilitating the proper assembly of iron-sulfur cluster-containing proteins, and regulating oxidative stress. ABCB8 is highly expressed in metabolically active tissues, such as the heart, skeletal muscle, and liver, where mitochondrial function is crucial. Dysregulation of ABCB8 can lead to mitochondrial iron overload, contributing to oxidative damage and cellular dysfunction, particularly in cardiomyocytes. Emerging evidence suggests that ABCB8 plays a protective role in maintaining mitochondrial integrity under stress conditions, making it an important factor in cardiovascular health and mitochondrial-related diseases.
Características del producto
category
ELISA Kits
immunogen target
ATP Binding Cassette Transporter B8 (ABCB8)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
EST328128,M-ABC1,MABC1,MITOSUR
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ABCB8
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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