Rat ATP Binding Cassette Subfamily B Member 4 (ABCB4) ELISA Kit

Este producto es parte de ABCB - ATP binding cassette subfamily B member
Rat ATP Binding Cassette Subfamily B Member 4 (ABCB4) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for ABCB4

proveedor

Abbexa

reference

abx514818

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat ATP Binding Cassette Subfamily B Member 4 (ABCB4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Multidrug resistance protein 3 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

ABCB4, also known as MDR3, is expressed on the canalicular membrane of hepatocytes and plays a pivotal role in bile formation by mediating the ATP-dependent translocation of phosphatidylcholine into bile. Phosphatidylcholine protects bile ducts from the detergent effects of bile salts, ensuring proper bile composition and preventing bile-related liver damage. Mutations in ABCB4 are associated with progressive familial intrahepatic cholestasis type 3 (PFIC3), low phospholipid-associated cholelithiasis (LPAC), and other cholestatic liver diseases. Dysregulation of ABCB4 leads to bile duct injury, inflammation, and fibrosis, ultimately resulting in liver dysfunction. As a critical regulator of bile composition, ABCB4 is a significant focus in the study of liver health and diseases related to bile metabolism.

Características del producto

category

ELISA Kits


immunogen target

ATP Binding Cassette Subfamily B Member 4 (ABCB4)


reactivity

Rat


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.07 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

ABC21,GBD1,ICP3,MDR2,MDR2/3,MDR3,PFIC-3,PGY3


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

ABCB4


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


Quizá le pueda interesar

Human ABCB4(Multidrug resistance protein 3) ELISA Kit

Human ABCB4(Multidrug resistance protein 3) ELISA Kit

proveedor

FineTest

reference

EH1170

reactivity

human

status

RUO

Precio a consultar

Ver más

ATP Binding Cassette Transporter B4 (ABCB4) Antibody (Biotin)

ATP Binding Cassette Transporter B4 (ABCB4) Antibody (Biotin)

proveedor

Abbexa

reference

abx105680

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Polyclonal

ATP Binding Cassette Transporter B4 (ABCB4) Antibody (Biotin) is a Rabbit Polyclonal antibody against ATP Binding Casset...

169€ (20 µg)

Ver más

ATP Binding Cassette Transporter B4 (ABCB4) Antibody (FITC)

ATP Binding Cassette Transporter B4 (ABCB4) Antibody (FITC)

proveedor

Abbexa

reference

abx107097

reactivity

Mouse

status

RUO

clonality

Polyclonal

ATP Binding Cassette Transporter B4 (ABCB4) Antibody (FITC) is a Rabbit Polyclonal antibody against ATP Binding Cassette...

169€ (20 µg)

Ver más