Rat Aryl Hydrocarbon Receptor Repressor (AHRR) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for AHRR
proveedor
Abbexareference
abx390994Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Aryl Hydrocarbon Receptor Repressor (AHRR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat AHRR concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
AHRR is a transcriptional repressor that negatively regulates the AHR signaling pathway. It is induced by AHR activation as part of a negative feedback loop and functions by competing with AHR for dimerization with ARNT or binding to XREs to inhibit AHR-mediated transcription. AHRR is expressed in various tissues, including the liver, lungs, and immune cells, and is involved in maintaining the balance of AHR activity, preventing excessive or prolonged responses to environmental toxins. Dysregulation of AHRR has been associated with cancer, particularly in lung cancer and gastric cancer, where reduced AHRR expression leads to enhanced AHR activity and tumor-promoting effects. In addition to its role in xenobiotic detoxification, AHRR also participates in regulating immune responses and maintaining cellular homeostasis, with emerging evidence highlighting its involvement in inflammation and metabolic disorders.
Características del producto
category
ELISA Kits
immunogen target
Aryl Hydrocarbon Receptor Repressor (AHRR)
reactivity
Rat
test range
78 pg/ml - 5000 pg/ml
sensitivity
< 46.9 pg/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
AHH,AHHR,bHLHe77
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
AHRR
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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