Human Aryl Hydrocarbon Receptor Repressor (AHRR) ELISA Kit

Este producto es parte de AHR - Aryl hydrocarbon receptor (repressor)
Human Aryl Hydrocarbon Receptor Repressor (AHRR) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for AHRR

proveedor

Abbexa

reference

abx150596

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Aryl Hydrocarbon Receptor Repressor (AHRR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Aryl Hydrocarbon Receptor Repressor (AHRR) concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Aryl Hydrocarbon Receptor Repressor (AHRR)


Background

AHRR is a transcriptional repressor that negatively regulates the AHR signaling pathway. It is induced by AHR activation as part of a negative feedback loop and functions by competing with AHR for dimerization with ARNT or binding to XREs to inhibit AHR-mediated transcription. AHRR is expressed in various tissues, including the liver, lungs, and immune cells, and is involved in maintaining the balance of AHR activity, preventing excessive or prolonged responses to environmental toxins. Dysregulation of AHRR has been associated with cancer, particularly in lung cancer and gastric cancer, where reduced AHRR expression leads to enhanced AHR activity and tumor-promoting effects. In addition to its role in xenobiotic detoxification, AHRR also participates in regulating immune responses and maintaining cellular homeostasis, with emerging evidence highlighting its involvement in inflammation and metabolic disorders.

Características del producto

category

ELISA Kits


immunogen target

Aryl Hydrocarbon Receptor Repressor (AHRR)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.06 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

AHH,AHHR,bHLHe77


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

AHRR


dry ice

No


NCBI accession

NP_001229341.1, NM_001242412.1


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


Quizá le pueda interesar

Aryl Hydrocarbon Receptor Repressor (AHRR) Antibody

Aryl Hydrocarbon Receptor Repressor (AHRR) Antibody

proveedor

Abbexa

reference

abx037882

Tested Applications

ELISA, WB, IHC

reactivity

Human

status

RUO

clonality

Polyclonal

Rabbit Polyclonal against the AHRR protein.

357.5€ (100 µg)

Ver más

Aryl Hydrocarbon Receptor Repressor (AHRR) Antibody

Aryl Hydrocarbon Receptor Repressor (AHRR) Antibody

proveedor

Abbexa

reference

abx130625

Tested Applications

WB, IHC, IF/ICC

reactivity

Human

status

RUO

clonality

Polyclonal

AHRR Antibody is a Rabbit Polyclonal against AHRR.

286€ (100 µl)

Ver más

Human Aryl Hydrocarbon Receptor Repressor (AHRR) ELISA Kit

Human Aryl Hydrocarbon Receptor Repressor (AHRR) ELISA Kit

proveedor

Abbexa

reference

abx150596

Tested Applications

ELISA

reactivity

Human

status

RUO

Human Aryl Hydrocarbon Receptor Repressor (AHRR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of ...

715€ (96 tests)

Ver más