Rat Annexin A2 (ANXA2) Protein
208€ (10 µg)
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Name
Rat Annexin A2 (ANXA2) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx652182
Tested Applications
WB, SDS-PAGE
Description
Rat Annexin A2 (ANXA2) Protein is a recombinant protein from Rat.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Annexin A2 (ANXA2) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Met1-Asp339 Tag: N-terminal His tag |
| Origin | Rat |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 42.4 kDa Observed MW (SDS-PAGE): 42 kDa |
| Expression | Recombinant |
| Purity | > 97% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q07936 |
| Alias | ANXA2,ANX2,ANX2L4,CAL1H |
| Background | Protein ANXA2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Endotoxin Level: <1.0 EU per 1µg (determined by the LAL method) Concentration: Prior to lyophilization: 200 µg/ml |
Background
ANXA2 is a calcium-dependent phospholipid-binding protein involved in membrane organization, endocytosis, and exocytosis. It plays critical roles in actin cytoskeleton remodeling, facilitating cell adhesion, migration, and vesicular trafficking. ANXA2 is also implicated in angiogenesis and fibrinolysis by serving as a co-receptor for plasminogen and tissue plasminogen activator (tPA), promoting fibrin degradation. Overexpression of ANXA2 has been linked to cancer progression, particularly in breast, lung, and colorectal cancers, where it enhances tumor cell migration, invasion, and metastasis. Additionally, ANXA2 is associated with viral replication, particularly in influenza and hepatitis viruses, making it a therapeutic target for infectious diseases and cancers.
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