Annexin A2 Phospho-Ser26 (ANXA2 pS26) Antibody
Pida mas información
935106861
info@markelab.com
Precio
52€ (10 µg)
Antibody anti-ANXA2
proveedor
Abbexareference
abx012741Tested Applications
ELISA, WBreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalDescripción
Rabbit polyclonal antibody against ANXA2 protein. Immunogen region is N-terminal. Specificity is as follows for the reactive species: H:S26, M:S26, R:S26.
Background
ANXA2 is a calcium-dependent phospholipid-binding protein involved in membrane organization, endocytosis, and exocytosis. It plays critical roles in actin cytoskeleton remodeling, facilitating cell adhesion, migration, and vesicular trafficking. ANXA2 is also implicated in angiogenesis and fibrinolysis by serving as a co-receptor for plasminogen and tissue plasminogen activator (tPA), promoting fibrin degradation. Overexpression of ANXA2 has been linked to cancer progression, particularly in breast, lung, and colorectal cancers, where it enhances tumor cell migration, invasion, and metastasis. Additionally, ANXA2 is associated with viral replication, particularly in influenza and hepatitis viruses, making it a therapeutic target for infectious diseases and cancers.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse, Rat
immunogen target
Annexin A2 Phospho-Ser26 (ANXA2 pS26)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB
purification
Purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
recommended dilution
ELISA: 1/10000, WB: 1/500 - 1/3000. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.
size 1
10 µg
size 2
100 µg
size 3
200 µg
size 4
300 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
ANXA2
dry ice
No
availability
Shipped within 5-10 working days.
alias
ANXA2,ANX2,ANX2L4,CAL1H
uniprot id
note
Concentration: 1 mg/ml -
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