Annexin A2 Phospho-Ser26 (ANXA2 pS26) Antibody
52€ (10 µg)
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935106861
info@markelab.com
name
Annexin A2 Phospho-Ser26 (ANXA2 pS26) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx012741
tested applications
ELISA, WB
Description
Rabbit polyclonal antibody against ANXA2 protein. Immunogen region is N-terminal. Specificity is as follows for the reactive species: H:S26, M:S26, R:S26.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Annexin A2 Phospho-Ser26 (ANXA2 pS26) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Data | Modification: Phosphorylation // Target Modification: Ser26 |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/3000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P07355 |
| Gene ID | 302 |
| Alias | ANXA2,ANX2,ANX2L4,CAL1H |
| Background | Antibody anti-ANXA2 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
ANXA2 is a calcium-dependent phospholipid-binding protein involved in membrane organization, endocytosis, and exocytosis. It plays critical roles in actin cytoskeleton remodeling, facilitating cell adhesion, migration, and vesicular trafficking. ANXA2 is also implicated in angiogenesis and fibrinolysis by serving as a co-receptor for plasminogen and tissue plasminogen activator (tPA), promoting fibrin degradation. Overexpression of ANXA2 has been linked to cancer progression, particularly in breast, lung, and colorectal cancers, where it enhances tumor cell migration, invasion, and metastasis. Additionally, ANXA2 is associated with viral replication, particularly in influenza and hepatitis viruses, making it a therapeutic target for infectious diseases and cancers.
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