Rat Ankyrin Repeat Domain-Containing Protein 16 (ANKRD16) ELISA Kit

Este producto es parte de ANKRD - Ankyrin repeat domain
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715€ (96 tests)

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935106861
info@markelab.com
name
Rat Ankyrin Repeat Domain-Containing Protein 16 (ANKRD16) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501849
tested applications
ELISA

Description

Rat Ankyrin Repeat Domain-Containing Protein 16 (ANKRD16) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Ankyrin repeat domain-containing protein 16 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Ankyrin Repeat Domain-Containing Protein 16 (ANKRD16)
Reactivity
Rat
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q499M5
Alias
ANKRD16
Background
Elisa kits for ANKRD16
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ANKRD16 is a protein containing multiple ankyrin repeat domains, which mediate protein-protein interactions and play key roles in cellular processes such as transcriptional regulation and protein stability. ANKRD16 has been identified as a tRNA splicing factor that interacts with components of the tRNA splicing machinery to ensure proper RNA maturation and protein synthesis. Loss of ANKRD16 function disrupts tRNA homeostasis, leading to the accumulation of defective RNA species and cellular stress. ANKRD16 is also involved in maintaining proteostasis and preventing the accumulation of misfolded proteins, which has been linked to neurodegenerative disorders. Recent studies suggest its role as a neuroprotective factor due to its ability to regulate tRNA quality control pathways, and mutations or dysregulation of ANKRD16 have been associated with neurodevelopmental diseases and certain cancers.
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