Rat Angiopoietin-Related Protein 1 (ANGPTL1) Protein
234€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Rat Angiopoietin-Related Protein 1 (ANGPTL1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx065328
tested applications
WB, SDS-PAGE
Description
Recombinant ANGPTL1 is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Angiopoietin-Related Protein 1 (ANGPTL1) |
| Host | E. coli |
| Origin | Rat |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 33.5 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Arg36-Leu297 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | D4A593 |
| Alias | ANG3,ANGPT3,ARP1 |
| Background | Protein ANGPTL1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ANGPTL1 is a member of the angiopoietin-like (ANGPTL) protein family, which regulates diverse biological processes, including angiogenesis, inflammation, and metabolism, although it does not interact with the Tie2 receptor like classical angiopoietins. ANGPTL1 functions as a tumor suppressor by inhibiting angiogenesis and cancer cell migration. It blocks endothelial cell proliferation and tube formation, reducing blood vessel growth within the tumor microenvironment. ANGPTL1 also regulates cell adhesion and extracellular matrix stability, contributing to tissue homeostasis and integrity. Reduced expression of ANGPTL1 has been observed in several cancers, including lung, liver, and colorectal cancers, where its loss is associated with tumor progression, metastasis, and poor prognosis. ANGPTL1 also plays a role in inhibiting inflammatory responses, linking it to immune regulation and vascular integrity. Its function as an anti-angiogenic and anti-tumor factor highlights ANGPTL1 as a promising therapeutic target for cancer treatment and vascular diseases.
Related Products
Human ANGPTL1 (Angiopoietin Like Protein 1) ELISA Kit
Ver Producto
Angiopoietin-Related Protein 1 (ANGPTL1) Antibody
Rabbit Polyclonal against the ANGPTL1 protein.
Ver Producto
Human Angiopoietin-Related Protein 1 (ANGPTL1) Protein
Human Angiopoietin-Related Protein 1 (ANGPTL1) Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Ver Producto