Rat Alpha Actinin 4 (ACTN4) ELISA Kit

Este producto es parte de ACTN - Actinin Alpha
Rat Alpha Actinin 4 (ACTN4) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for ACTN4

proveedor

Abbexa

reference

abx517033

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat Alpha Actinin 4 (ACTN4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Alpha Actinin 4 (ACTN4) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

ACTN4 encodes alpha-actinin-4, a non-muscle isoform of the actinin family that plays a critical role in cellular motility, adhesion, and signal transduction. It is widely expressed in various tissues, where it crosslinks actin filaments and interacts with focal adhesion proteins to regulate cytoskeletal organization and mechanotransduction. ACTN4 is particularly important in podocytes of the kidney, where it contributes to the maintenance of glomerular filtration barrier integrity. Mutations in ACTN4 are associated with focal segmental glomerulosclerosis (FSGS), a kidney disease characterized by proteinuria and progressive renal failure. In addition to its structural role, ACTN4 is implicated in cancer metastasis and cell invasion, reflecting its involvement in dynamic cellular processes. Its diverse functions in cytoskeletal dynamics and signal regulation highlight its importance in cellular stability and adaptability.

Características del producto

category

ELISA Kits


immunogen target

Alpha Actinin 4 (ACTN4)


reactivity

Rat


test range

78 pg/ml - 5000 pg/ml


sensitivity

< 39.2 pg/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

ACTN4,ACTININ-4,FSGS,FSGS1


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

ACTN4


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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