Rat Alanine Glyoxylate Aminotransferase 2 (AGXT2) Protein

221€ (10 µg)
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935106861
info@markelab.com
name
Rat Alanine Glyoxylate Aminotransferase 2 (AGXT2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx650510
tested applications
WB, SDS-PAGE
Description
Rat AGXT2 Protein is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Alanine Glyoxylate Aminotransferase 2 (AGXT2) |
| Host | E. coli |
| Origin | Rat |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 35.4 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met225-Lys512 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q64565 |
| Alias | AGXT2, AGT2 |
| Background | Protein AGXT2 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Alanine-glyoxylate aminotransferase 2 (AGXT2) is a mitochondrial enzyme that participates in the metabolism of amino acids, including the reversible conversion of glyoxylate and alanine to pyruvate and glycine. AGXT2 plays a role in cardiovascular health by metabolizing dimethylarginines, including asymmetric dimethylarginine (ADMA), an inhibitor of nitric oxide synthase and a biomarker for cardiovascular diseases. By reducing ADMA levels, AGXT2 contributes to the regulation of nitric oxide production and endothelial function. Dysregulation of AGXT2 is implicated in hypertension, atherosclerosis, and metabolic syndromes. In addition, AGXT2's role in glyoxylate metabolism links it to oxalate production, suggesting potential contributions to kidney stone formation and renal dysfunction in certain pathological contexts.
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