Rat Adrenocortical Dysplasia Homolog (ACD) Protein

Este producto es parte de ACD - Adrenocortical Dysplasia Homolog
Rat Adrenocortical Dysplasia Homolog (ACD) Protein

Pida mas información

935106861

info@markelab.com

Precio

234€ (10 µg)

Protein ACD

proveedor

Abbexa

reference

abx168867

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Rat ACD Protein is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).


Background

ACD, also known as TPP1, is a shelterin complex component involved in protecting telomeres and maintaining chromosomal stability. It regulates telomere length and integrity by recruiting telomerase and interacting with other shelterin proteins, such as POT1, to prevent inappropriate DNA damage responses at chromosome ends. ACD plays a critical role in cellular aging, genome stability, and cancer suppression. It is expressed in proliferative tissues, where telomere maintenance is essential for cellular replication. Dysregulation or mutations in ACD are associated with telomere-related disorders, such as dyskeratosis congenita and aplastic anemia, as well as increased susceptibility to cancer due to compromised chromosomal stability. ACD’s functions in telomere biology underscore its importance in aging, genome integrity, and disease prevention.

Características del producto

category

Proteins and Peptides


origin

Rat


host

E. coli


immunogen target

Adrenocortical Dysplasia Homolog (ACD)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 24.6 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Asn147-Glu342 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

ACD


dry ice

No


availability

Shipped within 5-7 working days.


alias

ACD,PIP1,PTOP,TINT1,TPP1,adrenocortical dysplasia homolog shelterin complex subunit and telomerase recruitment factor


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


Quizá le pueda interesar

anti- ACD antibody

anti- ACD antibody

proveedor

FineTest

reference

FNab00078

Tested Applications

ELISA, WB

reactivity

human

status

RUO

clonality

polyclonal

Component of the shelterin complex(telosome) that is involved in the regulation of telomere length and protection. Shelt...

Precio a consultar

Ver más

Adrenocortical Dysplasia Homolog (ACD) Antibody

Adrenocortical Dysplasia Homolog (ACD) Antibody

proveedor

Abbexa

reference

abx038018

Tested Applications

ELISA, WB

reactivity

Human

status

RUO

clonality

Polyclonal

Rabbit Polyclonal against the ACD protein.

357.5€ (100 µg)

Ver más

Adrenocortical Dysplasia Homolog (ACD) Antibody

Adrenocortical Dysplasia Homolog (ACD) Antibody

proveedor

Abbexa

reference

abx125486

Tested Applications

ELISA, WB

reactivity

Human

status

RUO

clonality

Polyclonal

ACD Antibody is a Rabbit Polyclonal against ACD.

195€ (20 µl)

Ver más