Rat Adrenocortical Dysplasia Homolog (ACD) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ACD
proveedor
Abbexareference
abx500661Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Adrenocortical Dysplasia Homolog (ACD) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Adrenocortical dysplasia protein homolog concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ACD, also known as TPP1, is a shelterin complex component involved in protecting telomeres and maintaining chromosomal stability. It regulates telomere length and integrity by recruiting telomerase and interacting with other shelterin proteins, such as POT1, to prevent inappropriate DNA damage responses at chromosome ends. ACD plays a critical role in cellular aging, genome stability, and cancer suppression. It is expressed in proliferative tissues, where telomere maintenance is essential for cellular replication. Dysregulation or mutations in ACD are associated with telomere-related disorders, such as dyskeratosis congenita and aplastic anemia, as well as increased susceptibility to cancer due to compromised chromosomal stability. ACD’s functions in telomere biology underscore its importance in aging, genome integrity, and disease prevention.
Características del producto
category
ELISA Kits
immunogen target
Adrenocortical Dysplasia Homolog (ACD)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
ACD,PIP1,PTOP,TINT1,TPP1,adrenocortical dysplasia homolog shelterin complex subunit and telomerase recruitment factor
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ACD
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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