Rat Acrosin (ACR) ELISA Kit
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935106861
info@markelab.com
Precio
643.5€ (96 tests)
Elisa kits for ACR
proveedor
Abbexareference
abx258769Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Acrosin (ACR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Acrosin (ACR) concentrations in tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Background
Acrosin (ACR) is a serine protease enzyme localized in the acrosome of spermatozoa, where it plays a critical role in the fertilization process. It is synthesized as an inactive zymogen called proacrosin, which is activated during the acrosome reaction to assist in the penetration of the sperm through the zona pellucida, the outer glycoprotein layer of the oocyte. Acrosin functions by hydrolyzing zona pellucida proteins and facilitating sperm binding to the egg, making it essential for successful fertilization. The activity of acrosin is tightly regulated to prevent premature activation, ensuring that it is only active during the fertilization process. Dysregulation or mutations affecting acrosin function have been associated with male infertility due to impaired sperm-oocyte interaction. Acrosin is also studied as a marker for sperm acrosomal integrity and functionality in reproductive biology and clinical diagnostics. Research into acrosin inhibitors is being explored as a potential strategy for developing non-hormonal contraceptives.
Características del producto
category
ELISA Kits
immunogen target
Acrosin (ACR)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.07 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
SPGF87
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ACR
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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